Fig. 1
From: Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome
Differentiated WBS-neurons represent all cortical layers of the brain and show normal neuronal morphology. Six week WBS A neuronal culture stained with dendritic marker (MAP2) alone (a) and together with neurofilament (NF-axonal marker) (b). c Fluidigm single cell qRT-PCR analysis to characterize the neurons and efficiency of the differentiation protocol. The depicted graph shows an average value of all WBS and WT neurons. d Distribution of generated neurons for various brain cortical layers based on marker gene expression profiles