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Fig. 1 | Molecular Brain

Fig. 1

From: Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain

Fig. 1

Intracolonic injection with zymosan induced visceral pain-like behaviors and enhanced expression of AMPA receptor in the ACC in mice. a The time course for injected with zymosan and behavioral test. b-d Mice injected with zymosan exhibited obvious visceral pain behavior (b), and reduced travel distance (c) and vertical counts (d) on day 1, 7, and 14 as compared with control. e Representative Western blot for GluA1 and GluA2/3 in the ACC obtained from control and zymosan-injected mice. f-g The expressions of GluA1 (f) and GluA2/3 (g) were significantly enhanced on day 1, 7, and 14 in the ACC of mice injected with zymosan as compared to those of control mice. N = 6 mice per group. * P < 0.05, ** P < 0.01 vs. control

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