Fig. 4From: The novel protein kinase C epsilon isoform modulates acetylcholine release in the rat neuromuscular junctionnPKCε and the mAChR signaling pathway in diaphragm muscles. Histogram shows changes in ACh release in the presence of mAChR blockers (PIR, 10 μM; MET, 1 μM; AT, 2 μM). We evaluated its effects in basal conditions and after a second incubation with CaC (2: CaC) or εV1-2 (2: εV1-2). We also preincubated with εV1-2 (1: εV1-2) and then blocked mAChR. * p < 0.05 vs. the corresponding controlBack to article page