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Fig. 2 | Molecular Brain

Fig. 2

From: Activation of protein kinase A in the amygdala modulates anxiety-like behaviors in social defeat exposed mice

Fig. 2

Clomipramine (CLI) relieved social avoidance and anxiety-like behavior. a Schematic representation of the SD and CLI administration protocol; b & c I.p. injection of CLI (10 mg/kg) increased the SIR (b) and decreased proportion of susceptible individuals (c) compared to the normal saline (NS) in the social interaction test (SIT); d & e CLI reversed SD stress-induced decreases in central-zone distance (d) and time (e) in open field test (OFT); f & g CLI reversed SD stress-induced decreases in both open-arm entries and time in elevated plus maze (EPM) test. *p < 0.05, **p < 0.01 verse NS control.

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