Fig. 5
From: Two di-leucine motifs regulate trafficking and function of mouse ASIC2a
Mutating the LL motifs increases acid-activated currents. CHO cells were transfected with wild-type (WT) and mutant ASIC2a as indicated. a–c Representative traces (a) and quantification of pH 4.5-actived current density (b), rate of activation (d), and rate of desensitization (d) for ASIC2a WT and mutants. N on the bars indicate total number of cells quantified. Astrerisks indicate significant differences from WT (p < 0.05, Kruskal-Wallis One Way Analysis of Variance on Ranks followed by Dunnett’s test)