Fig. 6
From: Two di-leucine motifs regulate trafficking and function of mouse ASIC2a
The DAA mutant shows increased pH sensitivity. Representative traces showing acid-activated current of ASIC2a WT, AAD and DAA at different stimulating pH. The plot shows pH sensitivity for the three constructs. pH50 for WT, AAD, and DAA was 4.53 ± 0.07, 4.64 ± 0.15, and 4.99 ± 0.07, respectively. The difference between WT and DAA was significant (p < 0.05). N = 5–6 per construct