Fig. 4

Hyperactivity in forced swim test in Sema3F KO mice. a, b Porsolt forced swim test. Mice were placed in a water-filled cylinder, and immobility time was measured every 1 min for a 10-min period on the first and second days. Sema3F KO mice spent significantly less time in immobility (a) and traveled significantly longer distances (b) than their WT controls. N = 19 for Sema3F KO mice; N = 20 for WT controls. c Tail suspension test. There was no significant difference in immobility between Sema3F KO mice and WT controls. All data indicate means ± SEM (n = 18 for Sema3F KO mice; n = 15 for WT controls)