Table 1 Summary of Atypical sensors and their ligands originating from bacterial pathogens
From: Atypical sensors for direct and rapid neuronal detection of bacterial pathogens
Sensors | Painful substances | Source bacteria | Gram-staining categories | References |
|---|---|---|---|---|
FPR1 | N-formyl peptides fMIFL | Staphylococcus aureus | (+) | Chiu et al. [14] |
FPR1 | N-formyl peptides fMLF | Streptococcus pneumoniae | (+) | Chiu et al. [14] |
FPR1 | N-formyl peptides fMIVIL | Listeria monocytogenes (predicted) | (+) | Chiu et al. [14] |
FPR1 | N-formyl peptides fMLF | Escherichia coli | (−) | Chiu et al. [14] |
TRPA1 | LPS (lipid A) | Escherichia coli | (−) | Meseguer et al. [47] |
TRPA1 | LPS (lipid A) | Salmonella typhimurium | (−) | Meseguer et al. [47] |
TRPA1 | LPS (lipid A) | Klebsiella pneumonia | (−) | Meseguer et al. [47] |
TRPA1 | LPS (lipid A) | Serratia marcescens | (−) | Meseguer et al. [47] |
TRPA1 | LPS (lipid A) | Pseudomonas aeruginosa | (−) | Meseguer et al. [47] |
TRPA1 | LPS (lipid A) | Rhodobacter sphaeroides | (−) | Meseguer et al. [47] |
ADAM10 | α-hemolysin | Staphylococcus aureus | (+) | Chiu et al. [14] |
AT2 | mycolactones | Mycobacterium ulcerans | (+) | Marion et al. [42] |