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Fig. 3 | Molecular Brain

Fig. 3

From: Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex

Fig. 3

Facilitatory effects of BDNF on persistent firing do not require de novo mRNA or protein synthesis. a Pre-incubation of slices with actinomycin D (ActD, 25 μM, 60 min) or cycloheximide (CHX, 1 μg/ml, 60 min) does not prevent BDNF facilitation of persistent firing induced by 5 μM CCh. Quantification of plateau potential amplitudes (b) and firing frequencies (c), * p < 0.05, ANOVA followed by Bonferroni multiple comparison

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Molecular Brain

ISSN: 1756-6606