Fig. 3
From: Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice
Analysis of spine density in CA1 of wild type and daDREAM mice. Analysis of spine densities in apical and basal dendrites of hippocampal CA1 neurons from wild type and daDREAM mice. a and b In apical dendrites, no difference between genotypes was observed using Sholl analysis (wt, n = 7; tg, n = 9). c and d In basal dendrites, a significant reduction in spine density in tg neurons was observed using Sholl analysis (wt, n = 7; tg, n = 9). e Total number of spines in the basal dendritic tree showing statistically significant lower number in daDREAM neurons (n = 8 mice in each group; Two-way ANOVA, P < 0.0011for genotype). Centered sixth order polynomial curve fitting was used (P < 0.0006)