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Fig. 2 | Molecular Brain

Fig. 2

From: The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity

Fig. 2

Sevoflurane and desflurane reduced co-localization of pre- and postsynaptic proteins. (a–i) Confocal images stained for postsynaptic PSD-95 (green) and presynaptic synaptophysin (red) in neurons 10 days post-culture exposed to sevoflurane and desflurane. (j) Quantification of number of PSD-95/synaptophysin positive puncta per μm of neurite. (k) Quantification of the mean fluorescence intensity of neurons stained for either PSD-95 or synaptophysin, normalized to the value in the control dish. One-way ANOVA: * p < 0.05, ** p < 0.01 as determined by pairwise comparison of the post-hoc tests. No asterisk indicates no statistical significance (p > 0.05). Scale bar 10 μm

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