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Fig. 5 | Molecular Brain

Fig. 5

From: The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity

Fig. 5

Sevoflurane and desflurane reduced spontaneous synaptic events and these effects were rescued by pre-treatment with Mdivi-1. (a–f) Representative patch clamping recording traces of spontaneous synaptic currents in neurons exposed to no anesthetic (control), desflurane, and sevoflurane alone or with Mdivi-1 (10 μM) pre-treatment, as indicated, recorded at 10 days post-culture. Spontaneous synaptic currents were isolated by adding tetrodotoxin (0.5 μM) in external solution

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