Fig. 6

Statistical data depicting the effects of sevoflurane and desflurane with and without Mdivi-1 pretreatment on the amplitude and frequency of spontaneous synaptic events. The mean spontaneous current amplitude was quantified in (a), and a cumulative probability plot of the event amplitude (pA) of all events recorded (minimum 400 events) in (b). Quantification of mean spontaneous current frequency (c) and a cumulative probability plot of the interevent interval (ms) of all events recorded (minimum 400 events) (d). Two-way ANOVA. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 as determined by pairwise comparison of the post-hoc tests; cumulative probability plot analyzed with Kolmogorov-Smirnov test