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Fig. 7 | Molecular Brain

Fig. 7

From: Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal

Fig. 7

A schematic diagram illustrating the novel function of VCP in ACD and apoptosis in HCN cells following insulin withdrawal. HCN cells undergo autophagic cell death following insulin withdrawal. In basal autophagy, VCP positively regulates autophagosome maturation. However, following insulin withdrawal, VCP regulates autophagy initiation and the crosstalk between ACD to apoptosis

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