Fig. 3

Low frequency and theta stimulations induce PS-LTP reconsolidation. a-b Low frequency-induced PS-LTP reconsolidation. d-e Theta stimulation-induced PS-LTP reconsolidation. Trace samples of recorded fEPSP signals recorded during the reactivation experiments with LFS0.1 (a), TS8 (d), or no reactivation (c). The average of the population spike (PS) amplitude recorded at each time point before and after LFS0.1 (b), TS8 (e), or no reactivation (b and e). Anisomycin (Ani) or PBS (Vehicle) was injected 5 min after reactivation or Ani injected without reactivation (Ani w/o React). n = 10–12 per group. RM two-way ANOVA, Newman-Keuls posthoc for within group test and Fisher’s LSD for between groups test (*p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001; ns, not significant (p > 0.05)). Error bars indicate SEM