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Fig. 7 | Molecular Brain

Fig. 7

From: Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

Fig. 7

Cooperative effects of ethanol and peroxide challenges on inflammasome markers NLRP3 and Casp1 in iPS cells. On day 7 following 24hr or 7d ethanol treatment, iPS cells were exposed for 14hr to 5 or 10μM H2O2 and immunostained with antibodies against NLRP3 and Casp1 (a), and LC3B (b). At 10μM H2O2, iPS cells pretreated with ethanol for 7d displayed a dramatic increase in death. Scale bars: 50 μm (a), 10μm (b)

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Molecular Brain

ISSN: 1756-6606