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Table 1 The intrinsic and extrinsic factors for the control of adult neurogenesis

From: Control of adult neurogenesis by programmed cell death in the mammalian brain

 

Cell types

References

Factors

NSC

Neuroblast

Immature neuron

Growth/Neurotrophic/Morphogenic factors

IGF-1

SGZ

 

DG

[53, 197–199]

Insulin

SGZ

  

[135, 180, 182]

NGF

  

DG

[204]

BDNF

  

DG

[205, 206]

Shh

SVZ

  

[228]

Wnt

SGZ

  

[226, 227, 230]

Steroid hormones

Progesterone

  

DG

[236]

Estrogen

SGZ

  

[231]

Prolactin

  

OB

[234]

Androgen

SGZ

 

DG

[232]

Neurotransmitters

Glutamate

OB, SVZ

SVZ

DG

[156, 166, 193, 211, 212]

GABA

 

DG

OB, DG

[213–215]

Serotonin

SGZ

 

DG

[216–218]

Dopamine

  

DG, OB

[219, 220]

Acetylcholine

  

DG, OB

[221–225]