Fig. 2
Effects of NONRATT021972 siRNA on the mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) in DM rats. a At the 4th week of the experiment, there was no difference in MWT among the groups. At the 6th week of experiment, the MWT in the DM, DM + NONRATT021972 si, and DM + NC si rats was decreased compared to the control rats. There was no significant difference among the DM, DM + NONRATT021972 si, and DM + NC si groups. One week after injection with NONRATT021972 si, the MWL in the DM + NONRATT021972 si group was higher than that in the DM group. n = 6,** p < 0.01 vs control group, # p < 0.05 vs DM group. b At the end of the 4th and 6th weeks of the experiment, the TWL in the DM, DM + NONRATT021972 si, and DM + NC si rats was lower than that in control rats. There was no significant difference among the DM, DM + NONRATT021972 si, and DM + NC si groups. One week after injection with NONRATT021972 si, the MWL in the DM + NONRATT021972 si group was higher than that in the DM group. n = 6,** p < 0.01, *** p < 0.001 vs control group, ### p < 0.001vs DM group