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Fig. 2 | Molecular Brain

Fig. 2

From: Histamine 1 receptor-Gβγ-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock

Fig. 2

H1R activation increases the cAMP level in the SCN through the Gβγ protein. Graph showing the effects on the content of cAMP in the mouse SCN tissue, of H1R (2-pyridylethylamine, 100 μM, n = 5 mice) and H2R (amthamine, 20 μM, n = 5 mice) agonists alone or in combination with the Gβγ inhibitor gallein (100 μM, n = 6 mice). Control: n = 5 mice. One-way ANOVA followed by Student-Newman-Keuls pairwise comparison test (*: p < 0.05)

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Molecular Brain

ISSN: 1756-6606