Fig. 6
From: Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media
ESC-M Reduces Lipid and Neutrophil Accumulation and Improves Locomotor Recovery. SCI mice were injected (i.p.) with ESC-M (n = 25) or CON-M (n = 17) (1 mL per mouse) after surgery and every 3rd subsequent day. a The locomotor function was assessed by Basso Mouse Scale (BMS) (ANOVA, p < 0.05). b Recovery of coordination in CON-M and ESC-M treated mice using chi square analysis for observed frequency. c The alternative horizontal ladder beam coordination based measure of locomotor activity on mice treated with CON-M or ESC-M. d Neutrophil accumulation was determined by detecting Gr-1+ cells in SCI mice treated with CON-M and ESC-M for 1 and 2 weeks (n = 4). e Lipid accumulation was determined by ORO staining in SCI mice treated with CON-M and ESC-M for 3 weeks (n = 4). (*p < 0.05) Data are represented as means ± SD