Table 1 The summary results of single marker association for the SNPs of GAS7 gene in two-stage study
Stage | Marker | Associated Allele | Frequency in Case | Frequency in Control | OR (95%CI) | P value |
|---|---|---|---|---|---|---|
1 | rs12450747 | A | 0.464 | 0.496 | 0.88 (0.78–0.99) | 0.036 |
rs11649731 | A | 0.585 | 0.558 | 1.12 (0.99–1.27) | 0.073 | |
rs12452356 | A | 0.876 | 0.895 | 0.83 (0.69–1.01) | 0.056 | |
rs9908211 | A | 0.268 | 0.222 | 1.28 (1.11–1.47) | 6.98E-4 | |
rs12150284 | C | 0.504 | 0.450 | 1.24 (1.10–1.40) | 5.90E-4 | |
rs11656696 | A | 0.481 | 0.533 | 0.81 (0.72–0.92) | 7.81E-4 | |
rs7208708 | C | 0.506 | 0.547 | 0.85 (0.75–0.96) | 0.0078 | |
2 | rs9908211 | A | 0.246 | 0.225 | 1.12 (1.03–1.23) | 0.012 |
rs12150284 | C | 0.487 | 0.452 | 1.15 (1.06–1.24) | 4.20E-4 | |
rs11656696 | A | 0.494 | 0.532 | 0.86 (0.80–0.93) | 1.69E-4 |