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Fig. 7 | Molecular Brain

Fig. 7

From: Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus

Fig. 7

Decrease in RGC numbers in AP-2δ−/− mice. a Retinal tissue sections at P0, P14, P21 and adult stages were stained with anti-Brn3a antibody and DAPI. Graphical representation of the changes in the number of Brn3a-positive RGCs in wild-type versus AP-2δ−/− eyes at P0, P14, P21 and adult. b Brn3a-positive cells relative to DAPI-stained cells were counted throughout the ganglion cell layer of multiple sections from each of the eyes analysed. Significance of differences in the percentages of Brn3a-positive cells was calculated using the non-parametric Mann–Whitney U-test. Abbreviations: WT, wild-type; KO, knock-out; S, significant; NS, not-significant

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