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Fig. 2 | Molecular Brain

Fig. 2

From: Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), adenosine receptors (A1 and A2A) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction

Fig. 2

Postnatal evolution of polyneuronal innervation. In a, comparison of the results of axon counts in fluorencence immunohistochemistry LAL preparations of YFP and C57BL/J6 mice. The histogram in b shows the percentage of singly-, dually- and triply- (or more) innervated synapses in YFP animals on the postnatal days studied without any experimental manipulation (control non-PBS, without subcutaneous injection), and also at P7, P9 and P15 after two (days 5–6), four (days 5–8) and ten (days 5–14) daily subcutaneous PBS applications respectively (control PBS). No differences are observed between PBS and non-PBS preparations (Fisher’s test: p > 0,05)

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