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Fig. 7 | Molecular Brain

Fig. 7

From: Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), adenosine receptors (A1 and A2A) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction

Fig. 7

Pre- and postsynaptic maturation in the MS3 clusters after stimulation and inhibition of the mAChRs. For each day considered (P7 in a, P9 in b and P15 in c) the figure shows the percentage of MS3 clusters (the oval nAChR plaques with fluorescence-free holes that mature at a faster rate) with one, two and three or more axons as an indication of the appropiate correspondence of the pre- and postsynaptic maturation. Fisher’s test * p < 0,05, ** p < 0,01, *** p < 0,005

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