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Fig. 4 | Molecular Brain

Fig. 4

From: Sex-dependent adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice

Fig. 4

5-HT1A-induced outward currents are unchanged in Deaf1-/- mice. Whole-cell voltage-clamp recordings of DRN 5-HT neurons from wild-type and Deaf-/- mice (n = 7 (3 male/4 female) and 6 (2 male/4 female) cells, respectively). a Time Course: 5-HT1A receptor-mediated outward current in response to 5-CT (100 nM; Vm = -55 mV). b 5-CT response: Average peak steady-state 5-HT1A-mediated currents from recorded 5-HT neurons in wild-type and Deaf1-/-tissues. Data are presented as mean ± SE

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