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Fig. 9 | Molecular Brain

Fig. 9

From: Differential arousal regulation by prokineticin 2 signaling in the nocturnal mouse and the diurnal monkey

Fig. 9

Differential effect of a PK2 antagonist PKR#7 on the locomotor activity and arousal levels in mice and monkeys. a. PKR#7 significantly increased the locomotor activity of the mice (N = 16, P < 0.05, Two-way ANOVA, *, P < 0.05, by Bonferroni’s post hoc test). b. PKRA83 significantly increased the wake time of the mice (N = 6, Two-way ANOVA, *, P < 0.05, by Bonferroni’s post hoc test). The inserts of A and B show the PKR#7 increased the locomotor activity and the wake minutes during the six hours day time period, respectively (**, P < 0.01, paired t-test). c. PKR#7 significantly increased the sleep time of the monkeys (N = 9, *, P < 0.05, paired t-test)

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Molecular Brain

ISSN: 1756-6606