Fig. 3
From: Hypothermia inhibits the propagation of acute ischemic injury by inhibiting HMGB1
Hypothermia reduces serum HMGB1 levels in MCAO rats. ELISA assay for HMGB1 performed on sera drawn from rats 4 h after sham or MCAO surgery in the absence or presence of hypothermia. The number of rats in each group was as follows: sham (n = 4), hypothermia (n = 4), MCAO (n = 4), MCAO + hypothermia (n = 4). ### P < 0.001 versus sham alone, *** P < 0.001 comparing MCAO with and without hypothermia, one-way analysis of variance (ANOVA) followed by the Bonferroni post hoc test