Fig. 2

Increased pThr514 CRMP2 correlates with Aβ₄₂ : Aβ₄₀ in LBD parietal cortex. a Bar graph of mean (± SEM) Aβ₄₂ to Aβ₄₀ ratios. Scatter plots of pThr514 CRMP2 with Aβ₄₂ : Aβ₄₀ in cytosolic fractions of b LBD (DLB + PDD), c DLB and d PDD parietal cortex, with insets indicating rho and p values. Where a correlation is significant, a best-fit regression line (solid line) is added together with its 95 % prediction intervals (dotted lines). Available N for control = 19; PDD = 19 and DLB = 20. ^§ p < 0.05; ^§§ p < 0.01, significant differences for multiple pair-wise comparisons (Kruskal-Wallis H with Dunn’s post-hoc tests). *p < 0.05; **p < 0.01, significant Spearman correlations