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Fig. 1 | Molecular Brain

Fig. 1

From: Heantos-4, a natural plant extract used in the treatment of drug addiction, modulates T-type calcium channels and thalamocortical burst-firing

Fig. 1

Heantos differentially modulates current density of T-type calcium channel isoforms. a Timecourse of action of Heantos (0.1 mg/ml) on individual T-type calcium channel isoforms (n = 5 per T-type isoform) exogenously expressed in HEK293 cells. b Representative traces of CaV3.1, CaV3.2 and CaV3.3 T-type calcium currents before and after Heantos application. c Histograms summarizing concentration-dependent action of Heantos on individual T-type calcium channel isoforms

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