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Fig. 4 | Molecular Brain

Fig. 4

From: The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture

Fig. 4

Enhanced delta power during NREM sleep in PLCβ4−/− mice. Normalized EEG power spectra for the δ (0.5–4 Hz), θ (4–9 Hz), σ (10–15 Hz), and α + β (9–20 Hz) frequency bands in wake, NREM sleep, and REM sleep during the light and dark phases. a, d In the awake state, the high-frequency power in the α + β band range did not differ between the two genotypes during both the light and dark phases. b, e In NREM sleep, the PLCβ4−/− mice showed significantly enhanced δ band power, while the σ-band power was not changed in both the light and dark phases. c, f The θ-band power was significantly decreased in REM sleep in the PLCβ4−/− mice during both the light and dark phases. All of the data are from the entire trace of each vigilance state appearing for 12 h in the PLCβ4+/+ (n = 8) and PLCβ4−/− mice (n = 9) and are presented as mean ± SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.005

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