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Fig. 6 | Molecular Brain

Fig. 6

From: The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture

Fig. 6

Increased NREM sleep amount and delta power in the TC-restricted PLCβ4 knockdown mice. a The total time spent in each vigilance state during the light and dark phases. The total amount of awake (W) did not differ between two groups during both the light and dark phases. Note that, the NREM (NR) sleep amount was increased in the TC-restricted PLCβ4 knockdown mice (PLCβ4 KD, white bar) compared to the control mice (black bar) during the light phase. The total amount of the REM (R) sleep was decreased during the dark phase in the PLCβ4 KD mice. b The PLCβ4 KD mice showed a significantly enhanced δ-band power with reduced σ-band power during the light phase. There was no difference in brain rhythms during NREM sleep in the dark phase. All of the data from the control (n = 6) and PLCβ4 KD mice (n = 6) are presented as mean ± SEM. *, p < 0.05

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