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Fig. 3 | Molecular Brain

Fig. 3

From: Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite

Fig. 3

Perturbed hypothalamic neurochemistry in PWS-IC mice. In situ hybridisation analysis of ARC Pomc, Agrp, Npy and Bdnf mRNA expression in PWS-IC mice demonstrates a significant decrease in ARC Pomc mRNA expression, but no effect on ARC Agrp, Npy and Bdnf mRNA levels. Data presented as Mean ± SEM. Student’s t-test, *p < 0.05, **p < 0.01, **p < 0.001 compared to WT controls

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Molecular Brain

ISSN: 1756-6606