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Fig. 4 | Molecular Brain

Fig. 4

From: Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite

Fig. 4

Blunted feeding effects of WAY-161503 in PWS-IC mice. 60 min food consumption upon administration of 3 mg/kg and 10 mg/kg WAY-161503 (s.c) in WT and PWS-IC mice. PWS-IC mice are unresponsive to an anorectic dose of the 5-HT2CR agonist WAY-161503. Data presented as Mean ± SEM, with statistical comparison performed by One-way repeated measure ANOVA, *p < 0.05 compared to vehicle controls

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