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Fig. 6 | Molecular Brain

Fig. 6

From: Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging

Fig. 6

Effects of intermittent hypoxia treatment (IHT) on pre- and post-synaptic proteins. a Effect of IH5D and IH5DR2 on levels of VGluT1, synaptophysin, GluA1, GluA2, PSD-95, and PICK1. Representative blots are shown for hippocampal TBS-insoluble fraction (left panels). Quantification data include the mean + SEM (n = 6) (right panels). b Quantification data for each postsynaptic protein in relation to PSD-95 in (a). Abbreviations: Ctrl = control group, IH5D = exposed to IHT for 5 days, IH5DR2 = exposed to IHT for 5 days, followed by normoxia treatment for 2 days. c Effect of IH28D on levels of VGluT1, synaptophysin, GluA1, GluA2, PSD-95, and PICK1. Representative blots are shown for hippocampal TBS-insoluble fractions (left panels). Quantification data include the mean + SEM (n = 7) (right panels). d Quantification data for each postsynaptic protein in relation to PSD-95 in (c). * p <0.05, ** p <0.01 vs. Ctrl. Abbreviations: Ctrl = reared at our institution for 28 days, IH28D = exposed to IHT for 28 days

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