Fig. 5From: Neuroligin 3 R451C mutation alters electroencephalography spectral activity in an animal model of autism spectrum disordersPower spectral profiles of WT and Nlgn3R451C mutant mice. The power of the individual frequency band (1 Hz bins) was normalized by expressing it as % of the average of total power (1-56 Hz for all epochs). Repeated measure two-way ANOVA using “genotype” and “frequency” as factors revealed significant genotype-frequency interaction for NREM sleep (F = 2.856, p <0.001). The NREM (B) spectral profile of Nlgn3R451C (KI) mice differed significantly between 2-8 Hz from WT mice (WT, n = 7; KI, n = 7; all p <0.05). More specifically, Nlgn3R451C mice had reduced powers between 2-8 Hz during NREM sleep (b) in comparison to WT mice. No significant genotype effect or genotype-frequency interactions were found for wake (a) and REM (c) statesBack to article page