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Table 2 Metabolic pathways implicated in clinical cases of ASD and IBD

From: Modeling environmental risk factors of autism in mice induces IBD-related gut microbial dysbiosis and hyperserotonemia

 

Pathway

vs. HC

Reference

ASD-related pathways

LPS/LPS proteins/Bacterial toxins

[45]

Steroid hormone biosynthesis

[42]

Ion channels/Pores ion channels

[59]

Inorganic ion transport and metabolism

[60]

Cell motility and secretion

[61]

Xylene degradation

[63]

Transporters

[64]

Dioxin degradation

[41]

Electron transfer carriers

[65]

IBD-related pathways

LPS/LPS proteins/Bacterial toxins

[46]

Sulfur metabolism

[43]

Glycosaminoglycan degradation

[67]

Geraniol degradation

[68]

N-Glycan biosynthesis

[44]

Benzoate degradation

[51]

Ether lipid metabolism

[69]

  1. Bold pathways are reported to be altered in both ASD and IBD