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Fig. 3 | Molecular Brain

Fig. 3

From: Turtle interacts with borderless in regulating glial extension and axon ensheathment

Fig. 3

Knockdown of tutl in R cells also disrupts glial extension. a-d WG processes and R-cell axons in third-instar eye-brain complexes were visualized with anti-Bdl (magenta) and MAb 24B10 (green), respectively. a and b In wild type, WG processes follow R-cell axons into the lamina (arrows). c and d When tutl was knocked down in R cells, but not in WG, WG extension in the lamina was disrupted. GMR-tutl-RNAi denotes that the UAS-tutl-RNAi transgene was under control of the eye-specific driver GMR-GAL4. e The length of individual WG extension within lamina was measured. Knockdown of tutl in R cells significantly disrupted WG extension (p = 2.17E-07). Two-tailed t-tests were used. Error bars indicate SEM. Number of individuals examined: wild type, 9; GMR-tutl-RNAi, 12. Scale bar: 20 μm

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