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Fig. 4 | Molecular Brain

Fig. 4

From: Turtle interacts with borderless in regulating glial extension and axon ensheathment

Fig. 4

tutl interacts genetically with bdl in the control of WG extension. a Reducing the dosage of bdl enhanced the WG extension phenotype in tutl k14703 hemizygotes. Flies in which the tutl k14703 allele was placed over a tutl deletion allele (i.e. tutl 23), showed a mild WG extension phenotype. This tutl k14703 hemizygote phenotype was significantly enhanced when the dosage of bdl was reduced by 50%. “****”, p < 0.00001. Two-tailed t-tests were used. Number of individuals examined: tutl k14703tutl, 9; tutl k14703tutl, bdl, 12. b Reducing the dosage of tutl enhanced the WG phenotype induced by mild overexpression of bdl in WG. Mild bdl overexpression in WG (i.e. bdl mild) did not affect WG extension. However, bdl mild-overexpression flies in which the dosage of tutl was reduced by 50%, displayed a strong WG extension phenotype. ns, not significant; “***”, p < 0.0001. One-way ANOVA analysis was used. Error bars indicate SEM. Number of individuals examined: wild type, 9; bdl mild; +/+, 13; tutl 23/+, 6; bdl mild; tutl 23/+, 15

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