Fig. 5
From: Turtle interacts with borderless in regulating glial extension and axon ensheathment
Blockade of FGF8 signaling in WG prevents WG processes from entering the optic stalk. Third-instar eye-brain complexes were double-stained with mCD8-GFP (green) and MAb 24B10 (red). a and b Wild type. c and d In flies with the expression of a dominant-negative form of htl under control of the WG-specific driver Mz97-GAL4 (n = 35), WG extension was severely disrupted. In flies showing the most severe phenotype (~14%), the majority of WG processes failed to enter the optic stalk (arrow), a phenotype that was never observed in bdl or tutl null mutants. “os” denotes optic stalk. Scale bar: 20 μm