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Fig. 5 | Molecular Brain

Fig. 5

From: Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens

Fig. 5

5-CSRTT performance in two independent cohorts reinforced with different isocaloric reward liquids. Behavioral outcomes from two separate cohorts of mice (n = 15–16/each cohort) of the same strain (C57BL/6) and age (6 months), assessed by independent labs (in Korea and the UK) with different isocaloric milk products (Additional file 2: Table S1) in the Bussey-Saksida touchscreen apparatus. a. Sessions to criterion, the number of sessions required to reach >80% accuracy and <20% omissions in baseline training (one-way ANOVA, F = 0.23, df = 1,30, p = 0.636). b. Accuracy (% of correct responses out of all responses made; mixed-effect model, main effect of group, F = 0.08, df = 1,29, p = 0.779; main effect of stimulus duration, F = 104.99, df = 3,455, p < 0.0001). c. Omission (% of trials missed out of all trials; main effect of group, F = 1.39, df = 1,29, p = 0.249; main effect of stimulus duration, F = 66.08, df = 3,455, p < 0.0001). YZ, Yazoo® used in UK cohort; SS, Seoul Strawberry milk® in Korean cohort

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