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Fig. 3 | Molecular Brain

Fig. 3

From: Increased biological activity of protein Kinase C gamma is not required in Spinocerebellar ataxia 14

Fig. 3

Illustration of PKCγ protein domain mutations and constructs for the experiments, a Map of 32 point mutations and deletions found in SCA14 families. Most mutations are found in the C1B domain. b Map of the seven point mutations and one deletion used in the transfection experiments in this study. c Vector map of the L7 expression vector used for Purkinje-cell specific expression of the transgenes. Each mutation or deletion was constructed as a GFP fusion protein

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