The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila

Table 1 Summary of mushroom body defects resulting from elav-GAL4 driven expression of UAS-Moe constructs

	Myc-Moe	Myc-MoeT559D	Moe-KD1	Moe-KD2	Myc-Moe; MoeKD1	Myc-Moe; MoeKD2
α/β lobes number^a	104	70	84	88	84	74
Axon stalling^b (%)	21	4	10	5	12	11
Lobe missing^c (%)	35	89	67	70	5	5
Abnormal morphology^d (%)	2	7	10	11	5	8
Normal morphology (%)	52	0	14	16	79	76
γ lobes number	38	40	37	42	37	39
Thinner (%)	11	100	8	14	3	5
Normal morphology (%)	89	0	92	86	97	95

^aThe percentage of each lobe phenotype was calculated from the total number of brain hemispheres analyzed for each genotype (n). ^bBrain hemispheres were scored as “axon stalling” when one or more partially elongated α/β lobes were present. ^cThe complete absence of one or more α/β lobes in a hemisphere was scored as “lobes missing”. ^dBrain hemispheres presenting any other defects of lobe morphology were scored as “abnormal morphology”

ISSN: 1756-6606