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Fig. 5 | Molecular Brain

Fig. 5

From: Role of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent model

Fig. 5

A Reasonable Hypothesis of GABAAR Subunit Plasticity Induced Within Two Days by One Dose of EtOH. Administration of EtOH to rats leads to changes of physio-pharmacological properties in GABAergic ionotropic receptor-mediated inhibitory synaptic transmission in hippocampus. The text at right of figure explains the time course of EtOH-induced plasticity, and how these same changes become persistent after CIE treatment. Reproduced from Lindemeyer et al. [30] with permission

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