Fig. 4

Behavioral abnormalities in T1KO. Significant differences were observed between genotypes in the six behavioral tests shown here. a General health (body weight; ****p < 0.0001), b Open field test (**p < 0.05), (c) Rota-rod test (**p < 0.05), d Acoustic startle responses (**p < 0.05), e General activity (**p < 0.05; ***p < 0.001), and f Social preference (stay time) (**p < 0.05; ***p < 0.001; ****p < 0.0001). Each group was composed of 20 male mice at the age of 12 weeks. See also Table 2