Fig. 2
From: Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors
The overexpression of PKMζ increases the immobile fraction of GluA2-containing AMPARs in both extrasynaptic and synaptic regions. The relative frequency distribution of diffusion coefficients of Qdot-labelled GluA2-containing AMPARs in neurons expressing PKMζ K98W (total: a, extrasynaptic: e, synaptic: i), T227E (total: c, extrasynaptic: g, synaptic: k), or control neurons (CTL) expressing mCerulean3.0-Homer1C alone (total: b, extrasynaptic: f, synaptic: j). Data are represented as mean ± standard deviation (S.D.) (d, h, l) Fraction of immobile receptors using the threshold in each set of experiment. Data were analyzed using a one-way analysis of variance (ANOVA), with post-hoc Newman Keuls multiple comparison test (* p < 0.05, ** p < 0.01). Data are represented as mean ± standard error of mean (S.E.M.)