From: Genomic copy number variation analysis in multiple system atrophy
GO set | Number of set genes | Number of CNV genes | p-value | q-value | |
---|---|---|---|---|---|
(a) Results of GO process analysis with CNVs included in exonic regions | |||||
GO:0007156 | homophilic cell adhesion via plasma-membrane adhesion molecule | 198 | 12 | 8.30e-11 | 1.71e-7 |
GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecule | 279 | 12 | 4.19e-9 | 4.31e-6 |
GO:0007155 | cell adhesion | 1706 | 24 | 3.23e-7 | 1.93e-4 |
GO:0022610 | biological adhesion | 1720 | 24 | 3.75e-7 | 1.93e-4 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 41 | 5 | 1.04e-6 | 3.44e-4 |
GO:0035872 | nucleotide-binding domain, leucine-rich repeat containing receptor signaling pathway | 42 | 5 | 1.17e-6 | 3.44e-4 |
(b) Results of GO process analysis with CNVs in intronic regions | |||||
GO:0014054 | positive regulation of gamma-aminobutyric acid secretion | 14 | 5 | 2.48e-9 | 5.48e-6 |
GO:0070777 | D-aspartate transport | 6 | 4 | 4.65e-9 | 5.48e-6 |
GO:0070779 | D-aspartate import | 6 | 4 | 4.65e-9 | 5.48e-6 |
GO:0014052 | regulation of gamma-aminobutyric acid secretion | 19 | 5 | 1.42e-8 | 7.39e-6 |
GO:0007268 | chemical synaptic transmission | 655 | 16 | 1.72e-8 | 7.39e-6 |
GO:0099537 | trans-synaptic signaling | 655 | 16 | 1.72e-8 | 7.39e-6 |