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Table 2 GO process analysis of copy number variants (CNVs) related to MSA

From: Genomic copy number variation analysis in multiple system atrophy

GO set Number of set genes Number of CNV genes p-value q-value
(a) Results of GO process analysis with CNVs included in exonic regions
GO:0007156 homophilic cell adhesion via plasma-membrane adhesion molecule 198 12 8.30e-11 1.71e-7
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecule 279 12 4.19e-9 4.31e-6
GO:0007155 cell adhesion 1706 24 3.23e-7 1.93e-4
GO:0022610 biological adhesion 1720 24 3.75e-7 1.93e-4
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 41 5 1.04e-6 3.44e-4
GO:0035872 nucleotide-binding domain, leucine-rich repeat containing receptor signaling pathway 42 5 1.17e-6 3.44e-4
(b) Results of GO process analysis with CNVs in intronic regions
GO:0014054 positive regulation of gamma-aminobutyric acid secretion 14 5 2.48e-9 5.48e-6
GO:0070777 D-aspartate transport 6 4 4.65e-9 5.48e-6
GO:0070779 D-aspartate import 6 4 4.65e-9 5.48e-6
GO:0014052 regulation of gamma-aminobutyric acid secretion 19 5 1.42e-8 7.39e-6
GO:0007268 chemical synaptic transmission 655 16 1.72e-8 7.39e-6
GO:0099537 trans-synaptic signaling 655 16 1.72e-8 7.39e-6