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Table 2 GO process analysis of copy number variants (CNVs) related to MSA

From: Genomic copy number variation analysis in multiple system atrophy

GO set

Number of set genes

Number of CNV genes

p-value

q-value

(a) Results of GO process analysis with CNVs included in exonic regions

GO:0007156

homophilic cell adhesion via plasma-membrane adhesion molecule

198

12

8.30e-11

1.71e-7

GO:0098742

cell-cell adhesion via plasma-membrane adhesion molecule

279

12

4.19e-9

4.31e-6

GO:0007155

cell adhesion

1706

24

3.23e-7

1.93e-4

GO:0022610

biological adhesion

1720

24

3.75e-7

1.93e-4

GO:0070423

nucleotide-binding oligomerization domain containing signaling pathway

41

5

1.04e-6

3.44e-4

GO:0035872

nucleotide-binding domain, leucine-rich repeat containing receptor signaling pathway

42

5

1.17e-6

3.44e-4

(b) Results of GO process analysis with CNVs in intronic regions

GO:0014054

positive regulation of gamma-aminobutyric acid secretion

14

5

2.48e-9

5.48e-6

GO:0070777

D-aspartate transport

6

4

4.65e-9

5.48e-6

GO:0070779

D-aspartate import

6

4

4.65e-9

5.48e-6

GO:0014052

regulation of gamma-aminobutyric acid secretion

19

5

1.42e-8

7.39e-6

GO:0007268

chemical synaptic transmission

655

16

1.72e-8

7.39e-6

GO:0099537

trans-synaptic signaling

655

16

1.72e-8

7.39e-6