Fig. 5

Decreased nuclear volume and increased neuronal density in Shn2 KO mice. (a, b) SEM images of cell bodies of granule cells in WT (a) and Shn2 KO (b) mice. Scale bars, 20 μm (c, d) Three-dimensional reconstruction of nuclear in granule cells of WT (c) and Shn2 KO (d) mice. (e) Comparison of neuronal density in WT (n = 3) and Shn2 KO (n = 3) mice. (f) Comparison of nuclear volume in WT (n = 120 from 3 mice) and Shn2 KO mice (n = 120 from 3 mice). The P-values were calculated using Student’s t-test (e) and Wilcoxon rank sum test (f)