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Fig. 3 | Molecular Brain

Fig. 3

From: Genetic dissection of the neuro-glio-vascular machinery in the adult brain

Fig. 3

CAV2 infects CAR-expressing cells contacting the cerebral vasculature. a Experimental timeline of CAV2-Cre intravenous injection. b Representative images of CAR expression in tdT+ cells in the hippocampus of RCL-tdT mice injected with intravenous CAV2-Cre. c Heat map of CAR distribution along astrocytic cells (measured as fluorescence intensity in arbitrary units) in the hippocampus. d Plot of CAR density on wrapping-type astrocytes of different regions (left), One-way ANOVA F(2,76) = 0.001, P = 0.999. Plot of CAR density on endfoot-type astrocytes of different regions (right), One-way ANOVA F(2,212) = 1.573, P = 0.210. e Representative images of CAR expression in GFAP+ cells in cortex. f Representative images of CAR expression in tdT+ cells in the molecular layer of the dentate gyrus. g Representative images of CAR expression in tdT+ cells in the hilus of the dentate gyrus. n = 3–4 animals per experiment. The scale bars are 10 μm

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