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Table 2 Glycine- and GABA-induced inward current and depolarization in IC and HC astrocytes

From: Expression of functional inhibitory neurotransmitter transporters GlyT1, GAT-1, and GAT-3 by astrocytes of inferior colliculus and hippocampus

Region

IGly (max) [pA]

P

IGABA (max) [pA]

P

Ratio

P

ΔEM (Gly) [mV]

P

ΔEM (GABA) [mV]

P

Ratio

P

IC

173 ± 28 (13)

0.200

n.s. sc

327 ± 35 (14)

0.009

* sc

1.9

0.002

** sc

3.0 ± 0.8 (8)

0.374

n.s. sc

7.2 ± 0.8 (7)

0.041

n.s. sc

2.4

0.003

** sc

HC

141 ± 20 (10)

504 ± 67 (7)

3.6

0.001

** sc

2.6 ± 0.5 (6)

10.6 ± 1.6 (7)

4.1

0.002

** sc

  1. The data are given as mean ± SEM. The number of experiments is given in parenthesis. IC Inferior colliculus, HC Hippocampus, P Probability value, sc Šidák corrected significance level for 2 comparisons, n.s. Not significant, *sc: P < 0.025, **P < 0.005. For critical significance levels, see Methods section