Fig. 4

Pro-inflammatory CKs and MT2 do not alter neuronal excitability in organotypic spinal slices. a Discharge patterns of ventral interneurons. The 500 ms depolarizing current commands induced different discharge patterns that identified four cell categories: transient, adapting, irregular and tonic. b Bar-charts illustrate the probability distribution (expressed as percentage of sampled population) of each cell type in the various conditions in the absence (left) or in the presence (right) of MT2. c Box-plots illustrate the absence of changes in the frequency of spontaneous action potentials in all conditions tested